This is a combination drug, a new generation antibiotic. Has a wide spectrum of action. Amoxiclav is used for prostatitis and in the postoperative period after removal of prostate adenoma to prevent the development of infections.
Release form and composition
Available in the form of tablets, powder for suspension and powder for the preparation of solution for intravenous administration. Intravenous administration is provided only in the hospital.
The composition of the medicine includes:
- Amoxicillin is an antibacterial agent from the first group of penicillins of semi-synthetic origin.
- Clavulanic acid – prevents the rapid destruction of amoxicillin in the body, enhances its effect.
Pills
Oval in shape, covered with a white film shell, perhaps a slight yellow tint. Available in three types, depending on the concentration of the main substance per tablet:
- amoxicillin 250, 500 and 875 mg;
- clavulanic acid 125 mg.
The composition also includes excipients: colloidal silicon dioxide, magnesium stearate, talc, crospovidone, croscarmellose sodium, cellulose.
For sale:
- 5, 7 and 14 pieces each, packed in a blister and supplied in cardboard boxes;
- 15, 20 and 21 pieces in bottles, packed in cardboard boxes.
Powder for preparing suspensions
White in color, with a slight yellow tint possible. Concentration of active ingredients per 5 ml of finished suspension:
- amoxicillin 125, 250 and 400 mg;
- clavulanic acid 31.25, 62.5 and 57 mg.
The following are used as excipients: citric acid, sodium citrate, cellulose, carmellose sodium, colloidal silicon dioxide, xanthan gum, silicon dioxide, flavorings, mannitol, sodium saccharinate.
It goes on sale in dark glass bottles of 8.75, 12.5, 17.5, 35 g. Packaged in a cardboard box with a dosing pipette.
pharmachologic effect
Many microorganisms are capable of producing beta-lactamase and are therefore resistant to most antibiotics. Due to the content of clavulanic acid in its composition, which blocks this enzyme, the effectiveness of Amoxiclav is higher than that of other drugs.
This bactericidal agent acts at the cellular level, which promotes the death of microorganisms.
Destroys most bacteria that can cause inflammation in the prostate gland:
- streptococci;
- enterococci;
- staphylococci;
- listeria;
- chlamydia;
- ureaplasma;
- Klebsiella
Amoxiclav is also effective for chronic prostatitis, because infections do not develop resistance to it.
Indications
The drug is used in the treatment of various diseases of bacterial origin:
- respiratory system and ENT organs;
- gastrointestinal tract;
- skin;
- venereal infections;
- infections of the genitourinary system.
In the treatment of inflammation of the prostate gland, the drug is effective for:
- treatment of acute and chronic forms;
- bacteria becoming resistant to other antibiotics;
- exacerbation of the calculous form of the disease.
Contraindications
This is a very strong antibiotic, so it has many contraindications. It should not be taken if:
- allergies to penicillin;
- intolerance to the components of the drug;
- cholestatic jaundice;
- infectious mononucleosis;
- oncological diseases of lymphatic tissue.
Use with caution in case of renal and hepatic insufficiency.
Before using the drug, you must inform your doctor if you are taking other medications.
In rare cases, side effects may occur that go away after stopping use. These include:
- loss of appetite;
- bowel dysfunction;
- nausea, vomiting;
- hives, itching.
Instructions for use
For prostatitis, the treatment regimen with Amoxiclav is determined individually, based on the patient’s physical characteristics and the degree of the disease.
Pills
The dosage of Amoxiclav for prostatitis directly depends on the form of the disease.
When treating uncomplicated forms of prostatitis, tablets with a concentration of the active substance of 250 or 500 mg are used.
For chronic prostatitis, Amoxiclav is prescribed in dosages of 500 and 875 mg. The dosage prescribed by the doctor is divided into 2 doses - morning and evening.
It is necessary to take Amoxiclav for prostatitis for 5-7 days. If the disease is severe, the duration of treatment may be increased.
For maximum effect, it is advisable to crush the tablets and dissolve them in water before using them. If this is not possible, you can chew it thoroughly and wash it down with water.
Powder for preparing suspensions
Typically, this form of the drug is prescribed for the acute stage of the disease, because it is absorbed more quickly by the body.
The dosage of the drug is calculated based on the patient’s weight category: 25-45 mg per 1 kg of weight.
The course of treatment of acute prostatitis with Amoxiclav lasts up to 14 days. Then you need to undergo a re-examination.
To prepare the suspension, the prescribed dose must be diluted with water, after shaking the bottle. The suspension must be taken immediately after preparation; the prepared solution cannot be stored.
Analogs
Analogues include:
- Ofloxacin.
- Ciprofloxacin.
- Augmentin.
- Panclave.
